Vittoriosa Stars moved temporarily in second place as they beat Lija Athletic 2-0 in one of the two matches in programme at the Luxol Stadium on Friday.
Luca Casha opened the score on the 12th minute and Joseph JoJo Ogunuppe made it 2-0 on the 27th.
On the other hand, Naxxar Lions returned to victory as they defeated San Gwann 4-1.
Duane Bonnici converted a penalty on the half-hour and scored another a minute later to put Naxxar two goals ahead. Jan Tanti scored thanks to a penalty on the 61st but Angus Buhagiar restored a two-goal lead for Naxxar on the 73rd and Duane Bonnici added another two minutes from time.
Santa Lucia lead the way with 14 points, followed by Vittoriosa, Mqabba and Sirens on 12, Lija 10, Pembroke, Zebbug 9, Qrendi 8, Gudja and Naxxar 7, Zejtun 6, Swieqi and Marsa 4 and San Gwann 0.