Marco Sansovini converted a penalty five minutes from the end of the first half to put Pescara ahead and Angelo Corsi doubled the score two minutes in added time.
The starting line-up for Malta: Andrew Hogg, Jonathan Caruana, Carlo Mamo, Gareth Sciberras, Massimo Grima, Roderick Briffa, Jamie Pace, Kevin Sammut, Shaun Bajada, Andrew Cohen, Michael Mifsud.