The Wanderers, on the other hand, were held in a 2-2 draw by Senglea, registered a comfortable win over Naxxar and then held Balzan in a goalless draw.
Meanwhile in the first match, Mosta and Tarxien Rainbows will both be all out to claim the three points.
The Blues lost to Valletta and Birkirkara but defeated Lija Athletic 3-1. On the other hand, the Rainbows are still chasing their first points after losing to Hamrun, Floriana and Gzira.