The Malta Football Association released the fixtures for the Women’s Knock-Out Competition 2021/22.
The first round will be played on May 17 and 18. The only team which is not involved in this round is Mtarfa who were awarded a bye.
The semi-finals are scheduled for May 22 while the final will be played on May 27.
| Tue-17-May | 19:45 | Centenary Stadium | Birkirkara | vs | Mgarr United |
| Tue-17-May | 19:00 | Mgarr Ground | Raiders Lija | vs | San Gwann |
| Wed-18-May | 19:45 | Centenary Stadium | Swieqi United | vs | Kirkop United |
| Sun-22-May | 16:00 | Centenary Stadium | Birkirkara or Mgarr | vs | Raiders Lija or San Gwann |
| Sun-22-May | 10:30 | Mgarr Ground | Swieqi or Kirkop | vs | Mtarfa |
| Fri-27-May | 19:30 | Centenary Stadium | Final |
Meanwhile the final of the Women’s Under-20 Knock-Out Competition between Raiders Lija and Birkirkara will be played on May 15 at the Centenary Stadium at 10:00 while the final of the Women’s Under-16 Knock-Out Competition between Swieqi United and San Gwann will be played on May 15 at the Marsaskala Ground at 10:00.