The Spartans lost 1-3 to Tarxien Rainbows last week and are now fourth on 16 points. With a win over the Wanderers, they would move third, one point behind the Rainbows although the latter would have a game in hand.
Sliema, on the other hand, are third from bottom on 11 points. They earned three points in three draws in their last three outings but have now gone seven matches without a win.
The Wanderers welcome back Julian Briffa, Clifford Gatt Baldacchino and John Mintoff who missed the last game against Marsaxlokk. Miguel Ciantar is in doubt after leaving the pitch injured.
In the first round, Sliema registered a 3-1 win.
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