The Citizens are coming from a series of six positive results, beating Balzan Youths and Marsaxlokk with an identical 2-0 score in their last two outings.
The Rainbows, on the other hand, are second from bottom with five points from eleven matches. They lost 0-3 to Sliema Wanderers after defeating Mqabba and Birkirkara in the previous games.
Rodrigo Galvao and Caio Garcia Suguino return for Tarxien after missing the game against Sliema. Valletta are expected to be in full strength.
In the first round, Valletta registered a 4-2 win.
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