SeasonRound1st Leg2nd LegAggregate
2021/22Q1BIRKIRKARA vs La Fiorita 1967 (SMR)1-01-1(2-1)
Q1UE Sant Julià (AND) vs GZIRA UNITED0-01-1(1-1)(3-5 pen)
Q1Mosta vs FK Spartak Trnava (SVK)3-20-23-4
Q2SS Folgore (SMR) vs Hibernians1-3
Q2Olimpija Ljubljana (SLO) vs Birkirkara1-0
Q2Gzira United vs HNK Rijeka (CRO)0-2

Notes:-

  • Names of local clubs in uppercase indicate that the club moved to the next round.
  • Teams eliminated from the UEFA Champions League preliminary and first qualifying round, enter the UEFA Europa Conference League.
  • As from 2021/22, the away-goals rule has been abolished.